What We Do
Quantitative imaging of cell therapies – re-imagined.
Cenya is developing imaging agents - BEACONS - to quantify cell therapies over extended periods of time. Quantification using medical imaging has traditionally required the use of radiopharmaceuticals. For safety reasons, these have short half-lives and stringent dosing limits thus only enabling quantification over short periods. Cenya BEACONS make use of stable, non-radioactive perfluorocarbon tracers which can quantify cells over far longer periods using non-proton MRI. Furthermore, BEACONS may be adapted to entrap radiopharmaceutical tracers, if users wish to use PET or SPECT in the short term, and MRI in the longer term.
Multimodal imaging – enabled.
Medical imaging is the only suitable non-invasive approach to tracking cells in patients, but individual imaging modalities (eg MRI, PET, Ultrasound) have trade-offs that prevent any one of them from yielding all the data needed by cell therapy developers.
Cenya’s BEACON technology solves this due to its inherent flexibility to incorporate a range of imaging agents suited to the medical imaging modality(ies) that will yield the data of most use to a specific cell therapy developer.
Cenya BEACONS can be used in the clinic
Follow your cells.
Assess cell biodistribution and pharmacokinetics.
Gain mechanistic understanding at the preclinical stage.
Study the effect of drugs or other factors on cell trafficking.
Directly move from a preclinical model to the clinic.
Pharmacokinetics
Cenya BEACONS can be used for in vivo quantification, with or without the use of radioligands, for extended lengths of time.
Multifunctional &
Multimodal
Cenya BEACONS can be used in clinical trials for MRI, fluorescence and photoacoustics (MSOT). Preclinically, BEACONS can include a radiotracer, cargo (e.g. drugs), targeting agents, and further modifications
Small Size
BEACONS are suitable for intracellular labeling, and can also be made for fast clearance.
Keep tabs on your cells.
Learn the science behind Cenya and how you can benefit.
